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Main equipment and specifications of the development plants
Onoda Plant (in Yamaguchi prefecture)
| Equipment | Size | Component | Quantity | Temp resistance (deg C) |
Remarks |
| Reactor | 100L | GL | 1 | -15～130 | |
| 200L | Teflon lining |
1 | -15～130 | ||
| 300L | Teflon lining |
1 | -15～80 | ||
| 500L | GL | 2 | -15～130 | ||
| 1,000L | SUS316L | 1 | -15～100 | ||
| 1,000L | GL | 1 | -15～130 | ||
| 2,000L | Teflon lining |
1 | -15～130 | ||
| 2,500L | Teflon lining |
1 | -15～130 | ||
| Cryogenic reactor |
20L | GL | 1 | -80～60 | |
| 40L | SUS316L | 1 | -80～60 | ||
| 100L | GL | 1 | -80～30 | ||
| 200L | GL | 1 | -80～30 | ||
| 500L | SUS316L, GL | 2 | -80～30 | ||
| Pressure reactor |
100L | GL | 1 | -15～130 | 0.98MPa |
| 500L | GL | 1 | -15～130 | 0.98MPa | |
| Crystallizer | 10L | GL | 1 | -15～130 | |
| 500L | Teflon lining |
1 | -15～130 | ||
| 500L | Teflon lining, GL |
2 | -15～130 | ||
| 1,000L | GL | 1 | -15～130 | ||
| 2,500L | Teflon lining |
1 | -15～130 | ||
| Pressure filter |
5L (0.03m2) |
SUS304 | 1 | RT | 0.2MPa |
| 20L (0.1m2) |
Teflon lining |
2 | RT | 0.2MPa | |
| 50L (0.1m2) |
GL | 1 | -15～80 | 0.2MPa | |
| 200L (0.4m2) |
GL | 1 | -15～80 | 0.2MPa | |
| 200L (0.4m2) |
GL | 1 | -15～80 | 0.2MPa | |
| 1200L (1m2) |
GL | 1 | -15～80 | 0.2MPa | |
| Filter dryer | 1000L (1m2) |
HASTELLOY C | 1 | -15～80 | FV～0.2MPa |
| 2500L (2m2) |
SUS316L | 1 | -15～80 | FV～0.2MPa | |
| Preparative HPLC |
200mmID × 1,000mmL |
SUS316 | 2 | RT | 1.5MPa |
| 450mmID × 1,000mmID |
SUS316 | 1 | RT | 1MPa | |
| 600mmID × 1,000mmL |
SUS316 | 1 | RT | 1.5MPa | |
| 600mmID × 1,500mmL |
SUS316 | 3 | 0～40 | 3MPa | |
| 800mmID × 2500mmID |
SUS316 | 1 | RT | 1MPa | |
| Other equipment | ・Film concentrator | GL | 3 | - | - |
| ・Evaporator 20L | GL | 3 | - | - | |
| ・Wall wetter 700L | GL | 1 | - | - | |
| ・High speed mixer | SUS304 | 1 | - | - | |
| ・Crusher | SUS316L | 1 | - | - | |
| ・Vibrating fluid bed dryer | SUS304 | 1 | - | - | |
| ・Freeze dryer | - | 1 | - | - |
Cryogenic reactor, 500 L
Clean room, Class 100,000
Preparative HPLC,
600mmID×1,000mmL
Other Nissan Chemical API Plant
Facilities for commercial production
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- Healthcare Division, Custom Chemicals
